Table 2.
Correlation between fibrinogen concentration and clinicopathological characteristics in gallbladder cancer patients n (%)
| Characteristics |
Fibrinogen concentration |
P value | |
| ≤ 3.47 g/L (n = 75) | > 3.47 g/L (n = 79) | ||
| Age (yr) | |||
| ≤ 60 | 31 (20.1) | 25 (16.2) | 0.243 |
| > 60 | 44 (28.6) | 54 (35.1) | |
| Sex | |||
| Male | 33 (21.4) | 30 (19.5) | 0.513 |
| Female | 42 (27.3) | 49 (31.8) | |
| Cholecystolithiasis | |||
| Absent | 38 (24.7) | 41 (26.6) | 0.878 |
| Present | 37 (24.0) | 38 (24.7) | |
| Diabetes | |||
| Absent | 57 (37.0) | 59 (38.3) | 0.850 |
| Present | 18 (11.7) | 20 (13.0) | |
| Jaundice | |||
| Absent | 68 (44.2) | 61 (39.6) | 0.029 |
| Present | 7 (4.5) | 18 (11.7) | |
| Blood groups | |||
| A | 19 (12.3) | 24 (15.6) | 0.145 |
| B | 33 (21.4) | 23 (14.9) | |
| AB | 2 (1.3) | 7 (4.5) | |
| O | 21 (13.6) | 25 (16.2) | |
| Pathological types | |||
| Adenosquamous carcinoma | 0 (0) | 3 (1.9) | 0.142 |
| Adenocarcinoma | 75 (48.7) | 75 (48.7) | |
| Papillocarcinoma | 0 (0) | 1 (0.6) | |
| Degree of differentiation | |||
| Poor | 23 (14.9) | 37 (24.0) | 0.048 |
| Moderate-well | 52 (33.8) | 42 (27.3) | |
| Resection margin status | |||
| Negative | 56 (36.4) | 40 (26.4) | 0.003 |
| Positive | 19 (12.3) | 39 (25.3) | |
| Maximum tumor diameter (cm) | |||
| ≤ 2.45 | 34 (22.1) | 34 (22.1) | 0.871 |
| > 2.45 | 41 (26.6) | 45 (29.2) | |
| T stage | |||
| Tis-T1a | 8 (5.2) | 2 (1.3) | < 0.001 |
| T1b-T2b | 22 (14.3) | 7 (4.5) | |
| T3 | 43 (27.9) | 60 (39.0) | |
| T4 | 2 (1.3) | 10 (6.5) | |
| N stage | |||
| N0 | 50 (32.5) | 48 (31.2) | 0.748 |
| N1 | 21 (13.6) | 26 (16.9) | |
| N2 | 4 (2.6) | 5 (3.2) | |
| Distant metastasis | |||
| Absent | 69 (44.8) | 73 (47.4) | 0.925 |
| Present | 6 (3.9) | 6 (3.9) | |
| TNM stage | |||
| 0-Istage | 12 (7.8) | 4 (2.6) | 0.011 |
| IIA-IIB stage | 12 (7.8) | 4 (2.6) | |
| IIIA-IIIB stage | 39 (25.3) | 53 (34.4) | |
| IVA-IVB stage | 12 (7.8) | 18 (11.7) | |
| CA199 (U/mL) | |||
| ≤ 39 | 41 (26.6) | 25 (16.2) | 0.005 |
| > 39 | 34 (22.1) | 54 (35.1) | |
| Albumin levels (g/L) | |||
| ≤ 40.5 | 32 (20.8) | 44 (28.6) | 0.111 |
| > 40.5 | 43 (27.9) | 35 (22.7) | |
| FAR | |||
| ≤ 0.08 | 59 (38.3) | 12 (7.8) | < 0.001 |
| > 0.08 | 16 (10.4) | 67 (43.5) | |
FAR: Fibrinogen to albumin ratio.