Table 5.
Univariate analysis of overall survival in gallbladder cancer patients
| Characteristics | HR (95%CI) | P value |
| Age (yr) | 1.473 (0.973-2.230) | 0.067 |
| ≤ 60 | ||
| > 60 | ||
| Sex | 0.995 (0.670-1.477) | 0.981 |
| Male | ||
| Female | ||
| Cholecystolithiasis | 1.198 (0.814-1.764) | 0.360 |
| Absent | ||
| Present | ||
| Diabetes | 1.028 (0.651-1.623) | 0.906 |
| Absent | ||
| Present | ||
| Jaundice | 2.598 (1.644-4.106) | < 0.001 |
| Absent | ||
| Present | ||
| Blood groups | - | 0.113 |
| A | ||
| B | ||
| AB | ||
| O | ||
| Pathological types | - | 0.165 |
| Adenosquamous carcinoma | ||
| Adenocarcinoma | ||
| Papillocarcinoma | ||
| Degree of differentiation | 1.527 (1.031-2.261) | 0.035 |
| Poor | ||
| Moderate-well | ||
| Resection margin status | 3.683 (2.468-5.496) | < 0.001 |
| Negative | ||
| Positive | ||
| Maximum tumor diameter (cm) | 1.101 (0.744-1.630) | 0.631 |
| ≤ 2.45 | ||
| > 2.45 | ||
| T stage | - | < 0.001 |
| Tis-T1a | ||
| T1b-T2b | ||
| T3 | ||
| T4 | ||
| N stage | - | < 0.001 |
| 0 | ||
| 1 | ||
| 2 | ||
| Distant metastasis | 2.550 (1.388-4.684) | 0.003 |
| Absent | ||
| Present | ||
| TNM stage | - | < 0.001 |
| 0-Istage | ||
| IIA-IIB stage | ||
| IIIA-IIIB stage | ||
| IVA-IVB stage | ||
| CA199 (U/mL) | 3.125 (2.010-4.858) | < 0.001 |
| ≤ 39 | ||
| > 39 | ||
| Fibrinogen concentration (g/L) | 2.795 (1.853-4.214) | < 0.001 |
| ≤ 3.47 | ||
| > 3.47 | ||
| Albumin levels (g/L) | 0.391(0.259-0.590) | < 0.001 |
| ≤ 40.5 | ||
| > 40.5 | ||
| FAR | 4.626(2.987-7.165) | < 0.001 |
| ≤ 0.08 | ||
| > 0.08 |
FAR: Fibrinogen to albumin ratio; HR: Hazard ratio; CI: Confidence interval.