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Synthesis and structure of TZ (XH-103). (a) The thiazolidine was reacted with bis(trichloromethyl) carbonate with triethylamine as base to prepare thiazolidine-3-carbonyl chloride. (b) Thiazolidine-3-carbonyl chloride was coupled with quercetin in the presence of triethylamine and 4-dimethylaminopyridine to afford the product TZ.
