Figure 7.

Preincubation with CoQ₁₀H₂ prevented H₂O₂ or HG-induced reduction in migration and tube formation by HUVECs. (a) Representative images of cell migration analysis evaluated using a wound-healing assay conducted over 12 hours in H₂O₂-induced reduction of migration. (b) Histograms show fold change in migration activity relative to control cells (n = 9). (c) Representative images from a H₂O₂-induced tube formation assay after a 6-hour incubation. (d) Histograms show fold change in total cell tube length relative to control cells (n = 6). (e) Representative images of cell migration over 12 hours evaluated using a wound-healing assay in HG-induced reduction of migration. (f) Histogram shows fold change in migration activity relative to control cells (n = 3). ^∗ P < 0.05, ^∗∗ P < 0.01, and ^∗∗∗ P < 0.001; mean ± SD, one-way ANOVA followed by Tukey's test.