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Western blot analysis of phosphorylated (p) and total S6K1 in pancreas tissue at the end of experiment. The ratio of thr-phosphorylation of S6K1 over total S6K1 increased in WD mice. SIT treatment reduced the ratio of p/total in WD mice significantly. ∗P < 0.05 compared to the CD group; #P < 0.05 compared to the WD group.
