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. 2018 Jun 25;10(8):e8736. doi: 10.15252/emmm.201708736

Figure 2. Loss of OGT in IECs causes intestinal damages in mice.

Figure 2

  1. Body weight of male wild‐type and Vil‐Ogt KO mice at 6 weeks of age (n = 6, P = 0.000015).
  2. Incidence of rectal prolapse in male wild‐type and Vil‐Ogt KO mice (WT n = 17, KO n = 9, P < 0.0001).
  3. Representative colonoscopy images of male wild‐type and Vil‐Ogt KO mice.
  4. Body weight of female wild‐type and Vil‐Ogt KO mice at 9 weeks of age (WT n = 11, heterozygous KO n = 4, homozygous KO n = 5, P < 0.0001).
  5. Incidence of rectal prolapse in female wild‐type and Vil‐Ogt KO mice (WT n = 9, heterozygous KO n = 8, homozygous KO n = 6, P = 0.0439).
  6. H&E staining of duodenum, jejunum, ileum, colon, and rectum of 10‐week‐old male wild‐type and Vil‐Ogt KO mice. Scale bars = 100 μm.
Data information: Data are represented as mean ± SEM. ***P < 0.001 by two‐tailed t‐test (A), Mantel–Cox test (B and E), or one‐way ANOVA with the Dunnett post hoc test (D).