Table 1.
Characteristics of patients with PA and EH.
| Essential hypertension | Primary aldosteronism | P value | |
|---|---|---|---|
| (n = 311) | (n = 174) | ||
| Gender (M/F) | 149/162 | 82/92 | 0.925 |
| APA (n, %) | — | 92, 51.7 | — |
| Age (years) | 47.77 ± 14.88 | 48.98 ± 12.41 | 0.364 |
| Duration of HT (years) | 3 (1, 7) | 7 (2, 12)∗ | 0.042 |
| History of diabetes (n) | 72 | 23 | 0.009 |
| History of CVD (n) | 18 | 23 | 0.006 |
| BMI (kg/m2) | 25.09 (22.69, 27.7) | 24.36 (22.3, 26.72) | 0.024 |
| SBP (mmHg) | 152.99 ± 21.54 | 157.10 ± 20.64 | 0.042 |
| DBP (mmHg) | 93.69 ± 15.63 | 96.50 ± 15.38 | 0.047 |
| Serum K+ (mmol/l) | 4.0 (3.8, 4.2) | 3.2 (2.7, 3.7) | <0.001 |
| Serum Na+ (mmol/l) | 142 (140, 143) | 143 (141, 145) | <0.001 |
| 24 h Urinary Na+ (mmol) | 140.6 (98.775, 204.75) | 153.15 (112.48, 208.95) | 0.244 |
| 24 h Urinary K+ (mmol) | 33.7 (25.35, 44.65) | 50.35 (34.68, 68.65) | <0.001 |
| PAC (ng/dl) | 11.00 (6.93, 17.20) | 29.30 (20.20, 53.08) | <0.001 |
| PRC (μIU/ml) | 17.20 (7.00, 35.40) | 1.95 (0.65, 4.85) | <0.001 |
| ARR | 0.63 (0.29, 1.47) | 17.19 (5.34, 54.67) | <0.001 |
Data were expressed as mean ± SD, %, or median (interquartile range). APA: aldosterone producing adenoma; HT: hypertension; CVD: cardiovascular disease; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; serum K+: concentration of serum potassium; serum Na+: concentration of serum sodium; PAC: plasma aldosterone concentration; PRC: plasma renin concentration.