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. 2018 Jul 12;2018:8751267. doi: 10.1155/2018/8751267

Figure 2.

Figure 2

Characterization of HFD-induced obesity model. Rats fed high-fat diet became significantly obese in the time course of body weight (a). Slightly increased glucose concentration in plasma in the HFD group after 10 weeks of high-fat diet feeding (b). Significantly increased insulin (c), HOMA-IR (d), triglyceride (e), and total cholesterol (f) concentration in the HFD group after 10 weeks of high-fat diet feeding. Slightly decreased HDL-C in the HFD group after 10 weeks of high-fat diet feeding (g). Taken together, the HFD rats developed insulin resistance in 10 weeks after high-fat diet feeding. P < 0.05; ∗∗ P < 0.01; ∗∗∗ P < 0.001 versus control.