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. 2018 Jul 13;8(3):2045894018791557. doi: 10.1177/2045894018791557

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© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 6. — Quantification of occlusive (a) and plexiform (PXL) lesions (c) and assessment of neomuscularization of small-size pulmonary arteries (b) in rats treated with either Sugen 5416 (SU Day 26 group; n = 8) or the combination of Sugen 5416 + 10 days of HAB treatment (Group SU+HAB Day 26; n = 8). The combination treatment resulted in development of numerous occlusive lesions in small-size (<50 μm) pulmonary arteries (a) and formation of PXL (d–f) similar to those seen in Sugen+hypoxia model (g).