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. 2018 Jul;16(6):786–848. doi: 10.2174/1570159X16666180308161642

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© 2018 Bentham Science Publishers

This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

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Fig. (8) — Structural detail of the interaction between mGluR₅ and antagonists/NAM. A) Complex between mGluR₅ and HTL14242 (PDBid 5CGD [382]); B) Complex between mGluR₂ and 3-chloro-4-fluoro-5-[6-(1H-pyrazol-1-yl)pyrimidin-4-yl]benzonitrile (PDBid 5CGC [382]).