Table 2.
Performance Parameters for the Dexcom G5 Mobile System and the FreeStyle Libre System When Compared Against BGMS Results Based on Aggregated Data
| DG5 (INT) | DG5 (LOCF) | FLcont. (INT) | FLscan | |
|---|---|---|---|---|
| MAD/MARD (complete experiments) versus capillary BGa | ||||
| MAD (<100 mg/dL), in mg/dL | 10.5 ± 10.7 (n = 2462) | 11.6 ± 11.5 (n = 2485) | 12.5 ± 11.0 (n = 2370) | 13.2 ± 11.6 (n = 2318) |
| MARD (≥100 mg/dL) | 10.3% ± 10.8% (n = 6991) | 11.3% ± 11.5% (n = 7048) | 10.5% ± 9.9% (n = 6486) | 11.3% ± 10.6% (n = 6323) |
| MAD/MARD (in house phases), based on max. one value per hour, versus capillary BGa,b | ||||
| MAD (<100 mg/dL), in mg/dL | 10.0 ± 11.1 (n = 947) | 11.0 ± 11.9 (n = 952) | 13.0 ± 11.1 (n = 932) | 13.2 ± 11.7 (n = 929) |
| MARD (≥100 mg/dL) | 9.4% ± 10.5% (n = 3516) | 10.2% ± 11.1% (n = 3541) | 10.4% ± 9.9% (n = 3324) | 11.0% ± 10.4% (n = 3288) |
| MAD/MARD (dynamic phases) versus capillary BGa | ||||
| MAD (<100 mg/dL), in mg/dL | 11.7 ± 12.2 (n = 822) | 13.0 ± 13.2 (n = 835) | 14.1 ± 11.5 (n = 775) | 15.2 ± 12.4 (n = 771) |
| MARD (≥100 mg/dL) | 12.4% ± 11.0% (n = 1752) | 13.5% ± 12.1% (n = 1762) | 12.3% ± 10.7% (n = 1622) | 13.7% ± 11.9% (n = 1620) |
| MAD/MARD (dynamic phases) versus venous BGa | ||||
| MAD (<100 mg/dL), in mg/dL | 13.1 ± 12.8 (n = 790) | 14.4 ± 14.0 (n = 803) | 14.9 ± 12.0 (n = 749) | 15.9 ± 12.7 (n = 745) |
| MARD (≥100 mg/dL) | 13.4% ± 11.6% (n = 1642) | 14.7% ± 12.7% (n = 1652) | 13.0% ± 11.4% (n = 1506) | 14.7% ± 12.8% (n = 1508) |
| MAD/MARD (home use phases) versus capillary BGa | ||||
| MAD (<100 mg/dL), in mg/dL | 10.0 ± 9.2 (n = 705) | 10.9 ± 9.7 (n = 712) | 10.4 ± 10.1 (n = 656) | 11.5 ± 10.7 (n = 616) |
| MARD (≥100 mg/dL) | 10.2% ± 10.1% (n = 1938) | 11.1% ± 10.7% (n = 1958) | 8.8% ± 8.4% (n = 1734) | 9.6% ± 8.8% (n = 1622) |
| Consensus error grid (complete experiments)a | ||||
| Zone A | 85.8% (n = 8114 of 9453) | 83.5% (n = 7964 of 9533) | 85.5% (n = 7575 of 8856) | 83.6% (n = 7225 of 8641) |
| Zone B | 13.8% (n = 1302 of 9453) | 16.0% n = 1521 of 9533) | 14.2% (n = 1261 of 8856) | 16.0% (n = 1386 of 8641) |
| PAD/PARD (complete experiments)c | ||||
| PAD (<100 mg/dL), in mg/dL | 8.3 ± 9.0 (n = 88172) | n.d.d | 12.1 ± 12.8 (n = 85435) | n.d.d |
| PARD (≥100 mg/dL) | 7.6% ± 8.3% (n = 289555) | n.d.d | 9.6% ± 10.3% (n = 241358) | n.d.d |
Because of differences between continuously stored and scanned FL data (FLcont and FLscan, respectively), separate analyses were performed.
Results given as mean ± standard deviation.
Comparison measurements were limited to up to one value per hour to not overrepresent the dynamic phases with one value every 15 min.
Analysis was performed on data with one value per minute obtained from linearly interpolating sensor readings.
Analysis was not performed.
INT, linearly interpolated data (interpolation of one value per minute); MAD, mean absolute difference; MARD, mean absolute relative difference; n.d., not done; PAD, precision absolute difference; PARD, precision absolute relative difference.