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. 2018 Feb 14;26(4):1082–1092. doi: 10.1016/j.ymthe.2018.02.008

Figure 5.

Figure 5

Amelioration of Muscle Ultrastructure through AAV-shDnm2 Injections

(A) Electron microscopy was used to assess the general ultrastructure of myofibers and to count the triads formed (yellow arrows, scale bar: 1 μm for left panels and 100 nm for right panels). (B) Graph representing the number of triad well formed and localized per sarcomere is shown (n = 3 per group). *p < 0.05; ***p < 0.001 for Mtm1KO treated with AAV-shRNA ctrl or AAV-shDnm2 versus WT treated with AAV-shRNA ctrl. $$$p < 0.001 Mtm1KO treated with AAV-shDnm2 versus Mtm1KO treated with AAV-shRNA ctrl (ANOVA test).