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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Int J Radiat Biol. 2017 Nov;93(11):1257–1266. doi: 10.1080/09553002.2017.1377360

Figure 4.

Figure 4.

Effect of fractionated whole brain irradiation on reactive oxygen species (ROS) generation in mouse brain. The localization of red fluorescence demonstrates ROS generation in mouse brain (A-D). Fractionated whole brain irradiation significantly increased superoxide anion formation in mouse brain (E). (A) Sham-irradiation (Control); (B) 4 h post-irradiation; (C) 8 h post-irradiation; (D) 24 h post-irradiation; (E) Quantitative analysis of fluorescence intensity. Data represent means ± SEM for each group (n=4). *p<0.05 compared to control. Scale bar: 100 μm.