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Quantification of mIPSCs for neurons from extracellular application of BDNF in AAV-Cre-eGFP-injected Dtnbp1F/F mice.
| Genotype and treatment | Group | Frequency (Hz) | Amplitude (pA) | Rise time (ms) | Decay time (ms) |
|---|---|---|---|---|---|
| WT + ACSF | Cre+ | 9.2 ± 0.4 | 37.7 ± 1.6 | 0.38 ± 0.01 | 4.5 ± 0.1 |
| Dtnbp1F/F +ACSF | Cre+ | 7.7 ± 0.4 | 37.0 ± 2.0 | 0.47 ± 0.02 | 5.9 ± 0.2 |
| Dtnbp1F/F +BDNF | Cre− | 10.0 ± 0.5 | 42.3 ± 1.9 | 0.42 ± 0.02 | 4.9 ± 0.1 |
| Cre+ | 10.2 ± 0.7 | 51.6 ± 2.2 | 0.39 ± 0.01 | 4.8 ± 0.1 |
