FIGURE 4.

Pharmacological DAGL inhibition does not affect unconditioned freezing. (A) Schematic diagram of the experimental paradigm. (B) (Far left panel) % freezing by C57BL/6J male mice during sham-conditioning assay-no shock was administered after tone. (Middle panels) % freezing during auditory cue during extinction training days 2 and 3. (Far right panel) % freezing during extinction recall (n = 15 male mice per condition). F- and P-values and η² for main effect of drug treatment shown in each panel. All values are presented as mean ± SEM.