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. 2018 Aug 6;11:455. doi: 10.1186/s13071-018-3027-x

Table 2.

Genetic polymorphisms and tests of neutrality for global PfMSP-142

Allele type/ Country (No. of sequences) K H Hd ± SD π ± SD dN-dS Tajima’s D (P-value)
Block15 Block16 Block17 Full Block15 Block16 Block17 Full
MAD20
 Myanmar
(n = 37)		 4.300 21 0.902 ± 0.040 0.00313 ± 0.00049 0.00272 ± 0.00035 0.00533 ± 0.00062 0.00351 ± 0.00033 0.0208 0.50117
(P>0.10)		 -0.65200
(P>0.10)		 0.23510
(P>0.10)		 -0.18385
(P>0.10)
 Thailand
(n = 29)		 2.620 6 0.473 ± 0.110 0.00153 ± 0.00048 0.00156 ± 0.00050 0.00364 ± 0.00094 0.00214 ± 0.00055 0.0027 0.25334
(P>0.10)		 -0.42016
(P>0.10)		 -0.53026
(P>0.10)		 -0.46786
(P>0.10)
 Philippines
(n = 24)		 3.880 5 0.652 ± 0.081 0.00268 ± 0.00018 0.00144 ± 0.00014 0.00694 ± 0.00082 0.00317 ± 0.00033 0.0040 1.57336
(P>0.10)		 1.89198
(0.05<P<0.10)		 2.22277
(P<0.05)		 2.60308
(P<0.01)
 PNG
(n = 44)		 4.098 7 0.753 ± 0.034 0.00263 ± 0.00011 0.00220 ± 0.00013 0.00607 ± 0.00029 0.00335 ± 0.00011 0.0035 1.67820
(P>0.10)		 0.80323
P>0.10		 1.99671
(0.05<P<0.10)		 1.84977
(0.05<P<0.10)
 SI
(n = 17)		 3.985 4 0.596 ± 0.099 0.00251 ± 0.00041 0.00205 ± 0.00036 0.00612 ± 0.00097 0.00326 ± 0.00052 0.0014 1.23804
(P>0.10)		 1.67363
(P>0.10)		 1.32924
(P>0.10)		 1.79153
(0.05<P<0.10)
 Vanuatu
(n = 48)		 2.052 3 0.228 ± 0.075 0.00116 ± 0.07200 0.00097 ± 0.00031 0.00339 ± 0.00110 0.00168 ± 0.00054 0.0019 -0.01160
(P>0.10)		 -0.01781
(P>0.10)		 -0.36701
(P>0.10)		 -0.25695
(P>0.10)
 Ghana
(n = 23)		 3.715 14 0.925 ± 0.041 0.00086 ± 0.00051 0.00324 ± 0.00019 0.00385 ± 0.00097 0.00304 ± 0.00029 0.0038 -0.66215
(P>0.10)		 1.91092
(0.05<P<0.10)		 -0.09195
(P>0.10)		 0.84400
(P>0.10)
 Tanzania
(n = 51)		 3.585 29 0.958 ± 0.014 0.00041 ± 0.00027 0.00296 ± 0.00028 0.00430 ± 0.00060 0.00293 ± 0.00023 0.0035 -1.46227
(P>0.10)		 0.05855
(P>0.10)		 0.25010
(P>0.10)		 -0.15863
(P>0.10)
K1
 Myanmar
(n = 18)		 1.431 6 0.765 ± 0.080 0.00214 ± 0.00037 0.00102 ± 0.00037 0.00093 ± 0.00042 0.00120 ± 0.00026 -0.0012 1.16615
(P>1.10)		 -1.34736
(P>0.10)		 -1.09629
(P>0.10)		 -1.00674
(P>0.10)
 Thailand
(n = 12)		 0.742 3 0.530 ± 0.136 0 0 0.00215 ± 0.00081 0.00062 ± 0.00023 0.0008 0 0 -0.82879
(P>0.10)		 -0.82879
(P>0.10)
RO33
 Myanmar
(n = 14)		 1.506 6 0.736 ± 0.109 0.00074 ± 0.00062 0.00115 ± 0.00039 0.00168 ± 0.00108 0.00123 ± 0.00041 0.0015 -1.15524
(P>0.10)		 -1.22200
(P>0.10)		 -1.79759
(P>0.10)		 -1.79616
(P>0.10)
 Thailand
(n = 33)		 2.375 6 0.680 ± 0.060 0.00088 ± 0.00043 0.00058 ± 0.00025 0.00529 ± 0.00055 0.00195 ± 0.00028 0.0024 -0.46603
(P>0.10)		 -1.04700
(P>0.10)		 1.23456
(P>0.10)		 0.21599
(P>0.10)
 Philippines
(n = 19)		 2.023 4 0.678 ± 0.088 0 0 0.00593 ± 0.00083 0.00166 ± 0.00023 0.0021 0 0 1.28875
(P>0.10)		 1.28875
(P>0.10)
 PNG
(n = 33)		 2.257 4 0.447 ± 0.093 0.00179 ± 0.00043 0.00144 ± 0.00030 0.00270 ± 0.00076 0.00185 ± 0.00047 0.0023 0.60324
(P>0.10)		 0.78518
(P>0.10)		 0.56203
(P>0.10)		 0.89252
(P>0.10)
 SI
(n = 24)		 0.811 3 0.236 ± 0.109 0.00118 ± 0.00053 0.00024 ± 0.00022 0.00122 ± 0.00110 0.00066 ± 0.00048 0.0008 -0.24844
(P>0.10)		 -1.51469
(P>0.10)		 -1.99611
(P<0.05)		 -1.99292
(P<0.05)
 Vanuatu
(n = 43)		 1.278 2 0.432 ± 0.057 0 0 0.00375 ± 0.00051 0.00106 ± 0.00014 0.0013 0 0 0.90772
(P>0.10)		 0.90772
(P>0.10)
 Ghana
(n = 10)		 4.022 6 0.844 ± 0.103 0.00242 ± 0.00068 0.00252 ± 0.00056 0.00534 ± 0.00144 0.00329 ± 0.00054 0.0041 0.81980
(P>0.10)		 0.86725
(P>0.10)		 0.12431
(P>0.10)		 0.61111
(P>0.10)
 Tanzania
(n = 20)		 3.694 13 0.953 ± 0.028 0 0.00250 ± 0.00030 0.00437 ± 0.00086 0.00303 ± 0.00032 0.0038 0 0.37812
(P>0.10)		 -0.37024
(P>0.10)		 0.03013
(P>0.10)

Abbreviations: K average number of pairwise nucleotide differences, Hd haplotype diversity, π observed average pairwise nucleotide diversity, dN rate of non-synonymous mutations, dS rate of synonymous mutations, PNG Papua New Guinea, SI Solomon Islands