Table 5.
Minimal inhibition concentration (μg/mL) of tested compounds.
Concentration (μg/mL) ± SE | ||||||
---|---|---|---|---|---|---|
Cryptococcus spp. | Candida albicans | |||||
Compound | 24 h | 48 h | 72 h | 24 h | 48 h | 72 h |
F1 | 6.5 ± 1.2* | 7.8 ± 0.5* | 7.4 ± 0.5* | – | – | – |
F2 | – | – | – | – | – | – |
L3 | ND | 33.3 ± 14.4 | – | ND | – | – |
L4 | ND | – | – | ND | – | – |
Fluconazole | 5.8 ± 1.4 | 9.2 ± 2.3 | 10.2 ± 3.2 | – | – | – |
SE, Standard error; –, Undistinguishable from DMSO alone (i.e., no effect); ND, Not determined;
F1 effect is undistinguishable from fluconazole effect against Cryptococcus spp., as assessed by t-test (p > 0.40 at all the times tested).