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. 2018 Jul 31;9:339. doi: 10.3389/fpsyt.2018.00339

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Copyright © 2018 Zhi, Calhoun, Lv, Ma, Ke, Fu, Du, Yang, Yang, Pan, Qi, Jiang, Yu and Sui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Group difference in network properties and three commonly identified abnormal FNCs. (A) Group difference in global efficiency and local efficiency in positive network (P) and negative network (N) (The asterisks indicate p < 0.05, FDR corrected). (B) Group difference in node strength and harmonic centrality (p < 0.001, FDR corrected), where the upward arrow and the down arrow represent increased and decreased node properties, respectively. (C) Three commonly identified FNCs in different states. Red lines represent increased FNCs while blue lines represent decreased FNCs in MDD patients. (D) The partial correlation between three commonly identified abnormal FNCs and symptom severity and cognitive performance.