Table 4.
Associations between individual Life’s Simple 7 components and incident atrial fibrillation among REGARDS participants*
| Component | n AF/N at risk | Model 1† OR (95% CI) |
Model 2‡ OR (95% CI) |
|---|---|---|---|
| Total cholesterol | |||
| Poor | 71/1,103 | 1 (Referent) | 1 (Referent) |
| Intermediate | 399/5,148 | 0.97 (0.74, 1.27) | 0.92 (0.70, 1.20) |
| Ideal | 255/3,325 | 1.02 (0.77, 1.36) | 1.04 (0.78, 1.37) |
| Blood pressure | |||
| Poor | 148/1,704 | 1 (Referent) | 1 (Referent) |
| Intermediate | 464/5,768 | 0.94 (0.77, 1.15) | 0.94 (0.77, 1.15) |
| Ideal | 113/2,104 | 0.68 (0.52, 0.89) | 0.70 (0.54, 0.92) |
| Blood glucose | |||
| Poor | 64/755 | 1 (Referent) | 1 (Referent) |
| Intermediate | 209/2,412 | 0.90 (0.67, 1.21) | 0.93 (0.69, 1.26) |
| Ideal | 452/6,409 | 0.73 (0.55, 0.97) | 0.79 (0.59, 1.04) |
| Physical activity | |||
| Poor | 195/2,743 | 1 (Referent) | 1 (Referent) |
| Intermediate | 270/3,827 | 0.98 (0.81, 1.20) | 0.99 (0.82, 1.21) |
| Ideal | 260/3,006 | 1.06 (0.87, 1.29) | 1.07 (0.87, 1.30) |
| Healthy diet score | |||
| Poor | 578/7,526 | 1 (Referent) | 1 (Referent) |
| Intermediate | 147/2,049 | 0.92 (0.76, 1.12) | 0.93 (0.77, 1.13) |
| Ideal | 0/1 | - | - |
| Smoker | |||
| Poor | 57/1,063 | 1 (Referent) | 1 (Referent) |
| Intermediate | 12/147 | 1.25 (0.65, 2.43) | 1.33 (0.69, 2.58) |
| Ideal | 656/8,366 | 1.13 (0.85, 1.51) | 1.17 (0.88, 1.56) |
| Body mass index | |||
| Poor | 272/3,445 | 1 (Referent) | 1 (Referent) |
| Intermediate | 295/3,699 | 0.75 (0.63, 0.90) | 0.76 (0.64, 0.91) |
| Ideal | 158/2,432 | 0.59 (0.47, 0.72) | 0.60 (0.49, 0.74) |
AF=atrial fibrillation, OR=odds ratio, CI=confidence interval
*
Results of multivariable logistic regression models
†
Model 1 adjusted for age, sex, race, education, income, and geographic region
‡
Model 2 adjusted for Model 1 + left ventricular hypertrophy, alcohol use, coronary heart disease, and stroke