Table 1.
Comparison between serum and prostate tissue levels of hormones and proteins in BPH patients
| Parameters | Serum concentration
|
Parameters | Concentration in prostate tissue | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SD | Min | Max | SD | Min | Max | ||||
| DHEAS (μg/mL) | 0.58 | 0.99 | 0.002 | 7.89 | DHEAS (pg/mg protein) | 5.04 | 3.06 | 0.81 | 15.94 |
| E2 (pg/mL) | 48.48 | 26.36 | 11.00 | 176.03 | E2 (pg/mg protein) | 0.02 | 0.01 | 0.00 | 0.06 |
| SHBG (nmol/L) | 44.15 | 17.33 | 8.19 | 107.37 | SHBG (pmol/mg protein) | 0.02 | 0.01 | 0.01 | 0.05 |
| LH (mIU/mL) | 8.17 | 5.70 | 0.90 | 38.53 | LH (mIU/mg protein) | 0.14 | 0.08 | 0.02 | 0.42 |
| TT (ng/mL) | 4.30 | 2.03 | 0.71 | 11.15 | TT (pg/mg protein) | 13.99 | 12.85 | 1.86 | 64.17 |
| TF (pg/mL) | 7.49 | 6.71 | 0.08 | 48.62 | TF (pg/mg protein) | 0.02 | 0.02 | 0.0002 | 0.12 |
| IGF-1 (ng/mL) | 85.75 | 36.18 | 33.81 | 361.90 | IGF-1 (ng/mg protein) | 0.36 | 0.24 | 0.02 | 1.309 |
| I (μIU/mL) | 15.83 | 12.86 | 0.10 | 62.88 | I (µg/mg protein) | 7.20×10−5 | 4.40×10−5 | 7.00×10−6 | 3.14×10−4 |
Note: , arithmetic average (Mann–Whitney U-test and Student’s t-test).
Abbreviations: BPH, benign prostatic hyperplasia; SD, standard deviation; Min, minimum; Max, maximum; DHEAS, dehydroepiandrosterone sulfate; E2, estradiol; SHBG, sex hormone binding globulin; LH, luteinizing hormone; TT, total testosterone; TF, free testosterone; IGF-1, insulin-like growth factor-1; I, insulin.