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. 2018 Jul 15;29(14):1682–1692. doi: 10.1091/mbc.E18-02-0141

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© 2018 Vittoria, Shenk, et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

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FIGURE 4: — miR-24 activates YAP through down-regulation of NF2. (A) Representative Western blot of NF2 protein levels in RPE-1 cells transfected with the indicated siRNA/miRNA after 48 h. (B) Quantification of Western blots in A. Error bars represent mean ± SEM (n > 3, ***p ≤ .001, ****p ≤ .0001, ns = nonsignificant, one-way ANOVA). (C) Representative fixed images of YAP localization in RPE-1 cells transfected with the indicated siRNA/miRNA after 48 h (n > 3). (D) Plot depicts the normalized ratio of YAP immunofluorescence intensity in the nucleus:cytoplasm (N/C) from C (n > 450 cells/condition, ****p ≤ .0001, one-way ANOVA).