Table I.
Diagnostic performance of the MAT
| Diagnostic cutoffs Parameters |
Optimal cutoff = 17.2% of CD63+ LAD2 cells | Cutoff to achieve 95% PPV = 17.2% CD63+ LAD2 cells | Cutoff to achieve 95% NPV = 0% CD63+ LAD2 cells | Optimal cutoff for severity = 24.8% CD63+ LAD2 cells |
|---|---|---|---|---|
| Sensitivity (%) | 73 (61-82) | 73 (61-82) | 99 (92-100) | 100 (57- 100) |
| Specificity (%) | 98 (92-99) | 98 (92-99) | 18 (12-28) | 87 (80-92) |
| PPV (%) | 96 (87-99) | 96 (87-99) | 48 (40-56) | 24 (11- 45) |
| NPV (%) | 83 (74-89) | 83 (74-89) | 94 (73-99) | 100 (97-100) |
Ninety-five percent CIs are indicated between parentheses.
PPV, Positive predictive value; NPV, negative predictive value.