Table E1.
Antibody levels and BAT and MAT results of the study population
| Median (IQR) | Patients with PA | Peanut-tolerant subjects |
P value∗ | |
|---|---|---|---|---|
| Peanut-sensitized but tolerant subjects | Non–peanut-sensitized, nonallergic subjects | |||
| Total IgE (KU/L), n = 157 | 324 (116.25 to 759) | 163 (49.5 to 572) | 43.5 (12.25 to 163.75) | .0850 |
| Specific IgE (KUA/L) | ||||
| Peanut, n = 173 | 14.05 (2.15 to 133.25) | 1.10 (0.33 to 3.36) | 0.01 (0.01 to 0.02) | <.0001 |
| Ara h 1, n = 169 | 0.27 (0.02 to 27.4) | 0.07 (0.01 to 0.34) | 0.01 (0.01 to 0.01) | .0029 |
| Ara h 2, n = 169 | 5.05 (0.39 to 54.5) | 0.07 (0.04 to 0.17) | 0.01 (0.01 to 0.03) | <.0001 |
| Ara h 3, n = 169 | 0.04 (0.01 to 1.07) | 0.05 (0.02 to 0.2) | 0.01 (0.01 to 0.01) | .7153 |
| Ara h 8, n = 168 | 0.04 (0.01 to 0.68) | 0.01 (0.01 to 0.20) | 0.01 (0.01 to 0.01) | .1953 |
| Ara h 9, n = 169 | 0.01 (0.01 to 0.07) | 0.02 (0.01 to 0.14) | 0.01 (0.01 to 0.01) | .0385 |
| BAT to peanut (% CD63+ basophils at 10-100 ng/mL peanut extract), n = 157 | 36.81 (13.06 to 62.81) | 0.5 (−0.01 to 1.79) | 0.2 (−0.02 to 0.68) | <.0001 |
| MAT (%CD63+ LAD2 cells at 1000 ng/mL peanut extract) | ||||
| Peanut, n = 153 | 28.9 (5.23 to 39.55) | 1.1 (−0.30 to 2.40) | 0.4 (−0.43 to 1.20) | <.0001 |
| Anti-IgE, n = 153 | 14.4 (8.975 to 21.53) | 17.4 (8.75 to 22) | 10.75 (6.8 to 16.73) | .5244 |
Medians and interquartile ranges are indicated. BAT and MAT results were corrected for the negative control.
IQR, Interquartile range.
∗
P values refer to the comparison between patients with PA and PS patients by using the Mann-Whitney U test.