Table 3. The effect of long-term (40-weeks) control of serum phosphate (serum P <4.5 vs P >4.5 mg/dl) on different variables.
| Variable | Week 40 P <4.5 mg/dL n = 12 | Week 40 P >4.5 mg/dL n = 9 | P* |
|---|---|---|---|
| Dialysis Duration (mins) a, § | 245.0 (243.0–247.5) | 246.0 (243.5–249.5) | 0.50 |
| KtV § | 1.9 (1.7–2.0) | 2.1 (1.8–2.3) | 0.27 |
| Kt (L/session) § | 61.4 (48.7–63.9) | 64.0 (53.5–67.5) | 0.24 |
| Albumin (g/L) | 3.6 (3.3–3.8) | 3.5 (3.3–3.9) | 0.88 |
| Hb (g/L) b, § | 11.9 (11.2–13.4) | 11.4 (10.7–12.0) | 0.19 |
| TSAT (%) c, § | 29.0 (23.7–46.0) | 25.0 (21.5–31.5) | 0.19 |
| Ferritin (ng/L) § | 500.5 (268.7–827.0) | 365.0 (173.5–655.5) | 0.27 |
| hs-CRP (mg/L) d, § | 4.1 (3.0–5.4) | 9.6 (5.2–15.) | 0.02 |
| Ca (mg/dL) e, § | 8.75 (8.31–8.91) | 8.65 (8.02–9.27) | 0.91 |
| iCa (mEq/L) fc6 § | 2.23 (2.20–2.25) | 2.20 (2.05–2.32) | 0.91 |
| P (mg/dL) g, § | 3.5 (2.7–3.9) | 5.3 (4.8–5.9) | <0.001 |
| iPTH (pg/ml) h, § | 199.0 (125.1–326.4) | 412.5 (325.0–541.2) | <0.01 |
| 25 (OH) D (ng/ml) i, § | 11.8 (8.10–14.8) | 8.29 (6.96–10.8) | 0.09 |
| 1,25 (OH)2 D (pg/ml) j, § | 7.8 (7.2–8.8) | 12.9 (5.2–14.4) | 0.31 |
| iFGF23 (pg/ml) k, § | 238.5 (131.7–443.5) | 1455.0 (884.0–1500.0) | <0.01 |
| cFGF23 (RU/ml) l, § | 864.5 (262.7–1299.5) | 3402.0 (1899.0–8875.0) | <0.001 |
a Dialysis Duration; Effective duration of the dialysis session
b Hb, Hemoglobin levels
c TSAT, Transferrin Saturation
d hs-CRP, C Reactive Protein
e Ca, Total serum Calcium
f iCa, Ionized Serum Calcium
g P, Serum Phosphate
h iPTH, Intact Parathyroid Hormone
i 25 (OH)D, 25 hydroxy vitamin D (calcidiol)
j 1,25 (OH)2 D, 1,25 dihydroxy vitamin D (calcitriol)
k i-FGF23, Intact Fibroblast Growth Factor 23
l c-FGF23, C-Terminal Fibroblast Growth Factor 23.
§ Median (IQR).
* P value