Skip to main content
. 2018 Apr 25;2018(4):CD007105. doi: 10.1002/14651858.CD007105.pub3
Methods Placebo‐controlled, RCT
Sequence generation not described
Follow‐up for 3 months
Participants Participants: 84 adults in a university setting in Korea
Operation: robot‐assisted thyroidectomy
2 groups, size: 41/43
Age (± SD), group 1, 2: not described
Men/women, group 1, 2: not described
Exclusion criteria: not described
Interventions Group 1 (lidocaine): after induction of anaesthesia, participants received a bolus of 2 mg/kg of lidocaine intravenously followed by continuous infusion at a rate of 3 mg/kg/h during surgery. Further details of anaesthetic regimen were not provided.
Group 2 (control): same as above except 0.9% saline was substituted for lidocaine.
Adjuvants: none
Immediate post‐op pain control: no improvement
Outcomes Dichotomous: pain vs no pain
Continuous: none
Other reported: quality of recovery and pain scores during 24 h and 48 h postoperatively
Notes Study published only as an abstract. We were unable to obtain additional information about methods, randomization or blinding methods from the study author.
Funding sources: funding of study not described
Conflicts of interest: conflicts of interest statement not provided
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Patients were "randomly allocated" but no further description of sequence generation was included
Allocation concealment (selection bias) Unclear risk Concealment of allocation not described
Blinding of participants and personnel (performance bias) All outcomes Unclear risk Blinding of participants and personnel not described
Blinding of outcome assessment (detection bias) All outcomes Unclear risk Blinding of outcome assessors not described
Incomplete outcome data (attrition bias) All outcomes Unclear risk Degree of attrition not described
Selective reporting (reporting bias) Unclear risk Use of subgroup analysis not described
Null bias High risk Quote: "pain scores for 2 days after surgery were not different between the two groups."