Methods | Placebo‐controlled, RCT Sequence generation not described Follow‐up for 3 months |
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Participants | Participants: 84 adults in a university setting in Korea Operation: robot‐assisted thyroidectomy 2 groups, size: 41/43 Age (± SD), group 1, 2: not described Men/women, group 1, 2: not described Exclusion criteria: not described |
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Interventions |
Group 1 (lidocaine): after induction of anaesthesia, participants received a bolus of 2 mg/kg of lidocaine intravenously followed by continuous infusion at a rate of 3 mg/kg/h during surgery. Further details of anaesthetic regimen were not provided. Group 2 (control): same as above except 0.9% saline was substituted for lidocaine. Adjuvants: none Immediate post‐op pain control: no improvement |
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Outcomes | Dichotomous: pain vs no pain Continuous: none Other reported: quality of recovery and pain scores during 24 h and 48 h postoperatively |
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Notes | Study published only as an abstract. We were unable to obtain additional information about methods, randomization or blinding methods from the study author. Funding sources: funding of study not described Conflicts of interest: conflicts of interest statement not provided |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Patients were "randomly allocated" but no further description of sequence generation was included |
Allocation concealment (selection bias) | Unclear risk | Concealment of allocation not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Blinding of participants and personnel not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Blinding of outcome assessors not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Degree of attrition not described |
Selective reporting (reporting bias) | Unclear risk | Use of subgroup analysis not described |
Null bias | High risk | Quote: "pain scores for 2 days after surgery were not different between the two groups." |