Table 3.
Comparison of patients with and without IDD
| IDD (+), n=46 | IDD (−), n=90 | P-valueb | |
|---|---|---|---|
| Age (years)a | 26.8±11.0; 23 (16–66) | 37.7±14.7; 33.5 (16–79) | <0.001 |
| Gender (male) | 22 (47.8%) | 48 (53.3%) | 0.59 |
| Follow-upa | 15.3±12.9; 11 (1–38) | 15.3±11.1; 12 (1–38) | 0.67 |
| LCM dosea | 337.0±67.0; 325 (200–400) | 316.7±66.2; 300 (200–400) | 0.07 |
| Use of concomitant SCB | 30 (65.2%) | 48 (53.3%) | 0.20 |
| Background AED, na | 2.07±0.90; 2 (1–4) | 1.62±0.57; 2 (1–3) | 0.006 |
| Side effect | 16 (34.8%) | 23 (25.6%) | 0.32 |
Notes:
a
Continuous variables are defined as mean ± SD and median (minimum–maximum), respectively.
b
Mann–Whitney U test was used for the comparison of continuous variables.
Abbreviations: Background AED nr, number of initial antiepileptic drugs; IDD, intellectual/developmental disorders; LCM, lacosamide; concomitant SCB, concomitant traditional sodium channel blocking agent.