Table 4. Percent contribution of TTXs, NaV1.8, and NaV1.9 to L-type CMH heat response changes with temperature (referring to insets in Fig. 11, A and B).
NaV channel | Temperature (±3°C) | ||||
---|---|---|---|---|---|
38°C | 41°C | 44°C | 47°C | 50°C | |
TTXs (C57BL/6J) | 36.8 | 33.3 | 31.2 | 8.7 | 1.8 |
TTXr (C57BL/6J) | 63.2 | 66.6 | 68.8 | 91.3 | 98.2 |
NaV1.8 + TTXs (NaV1.9−/−) | 73.2 | 85.5 | 70.0 | 39.7 | 32.8 |
NaV1.9 + TTXs (NaV1.8−/−) | 26.8 | 14.5 | 30.0 | 60.3 | 67.2 |