Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 6;215(8):1975–1986. doi: 10.1084/jem.20180518

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Blanc et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Figure 5. — Effect of PZA on the extent of bacterial killing or CEQ/CFU ratio at the lesion level in cellular lesions (A), necrotic lesions (B), and uninvolved lung (C). To visualize the effect of PZA-mediated bacterial killing in addition to killing by the immune system, the data are presented as log CEQ/CFU ratio assigned to bins in 0.5-log increments in untreated rabbits (gray bars, immune killing only) and drug treated rabbits (blue bars, combined immune and PZA-mediated kill). Statistical analyses were performed by using nonlog normalized values. Data points where both CFU and CEQ values were below the LOD were excluded from this analysis. Data from two independent experiments were combined to generate the plots. Asterisks indicate statistically significant differences between the PZA treated and untreated groups by using the two-tailed Mann-Whitney U test (used to compare the CEQ/CFU ratios before log transformation and before binning). *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001.