Figure 7.
Downstream signal networks of TLR3, TLR7, and TLR8 in neurons differ. (A) Venn diagram showing the overlap between TLR3, TLR7, and TLR8 up-regulated (left) and down-regulated (right) genes. Gene lists showing overlap among and between TLR3, TLR7, and TLR8 are available in Table S1. (B) GO of the biological functions for up-regulated and down-regulated genes from TLR3, TLR7, and TLR8 activation. Only four biological processes in the group of TLR8 up-regulated genes were identified. The top five GO biological processes of the rest of the groups are listed. Gene lists of each GO are available in Table S2.