Table 5. Parameters used to model MT growth.

Parameter	Description	Value
r0	Width of energy potential well characterizing the length of tubulin–tubulin bond	0.13 nm
alat	Energy parameter for lateral repulsion; corresponds with ∼2 × height of the energy barrier for lateral bond	15 kBT = 9 kcal/mol
blat	Depth of the potential well for lateral bonds	5.3 kBT = 3.2 kcal/mol for MT growth
		4.3 kBT = 2.6 kcal/mol for MT shortening
along	Energy parameter for longitudinal repulsion; corresponds with ∼2 × height of the energy barrier for longitudinal interdimer bond	15 kBT = 9 kcal/mol
blong	Depth of the potential well for longitudinal interdimer bond	16.6 kBT = 10 kcal/mol
k	Stiffness of longitudinal intradimer bond	517 kBT nm−2 = 310 kcal/mol nm−2
B	Flexural rigidity of PF bending	58 kBT rad−2 = 35 kcal/mol rad−2
χD0	Equilibrium angle between GDP-tubulin monomers	0.2 rad
χT0	Equilibrium angle between GTP-tubulin monomers	0.2 rad
ctub	Soluble tubulin concentration	10 µM
kon	On-rate constant for tubulin addition	8.3 µM−1s−1 per MT
T	Temperature	310 K
η	Viscosity	0.2 Pa · s
dt	time step for dynamic algorithm	10−10 s
Tkin	time step for kinetic algorithm	10−3 s