Figure 2. Odorant receptor (OR) gene family phylogeny including representatives of all apterygote and paleopteran insect orders.
The Maximum Likelihood tree demonstrates monophyly of the single-copy insect Orco with high bootstrap support. The M. hrabei genome lacks Orco but encodes five ORs clustering in a single highly-supported clade. T. domestica has a fully developed functional OR/Orco system. The red arrowheads indicate the locations of the three T. domestica ORs identified by Missbach et al. (2014), including the gene identified as T. domestica Orco in this study (formerly TdomOrco2).