Table 1.
Characteristics of HIV-infected children experiencing therapeutic failure.
| Characteristic | |
|---|---|
|
| |
| Median age (years) | 7 |
| Gender | |
| Male | 13 (59.1) |
| Female | 9 (40.9) |
| CDC (Category C)a | 2 (9.1%) |
| CDC (AIDS-defining conditions)a | 2 (9.1%) |
| Virologic failureb and documented resistance | 22 (86.4%) |
| Median CD4 count and range (cells/m3) | 817 (134–1885) |
| Median HIV-RNA viral load and range (copies/mL) | 1352 (1100–20 202) |
| Inadequate adherence to ARVs | 20/22 (91%) |
Values are number (%) unless otherwise indicated.
a
The Centers for Disease Control and Prevention (CDC). Clinical categories for children younger than 13 years (Category C= HIV encephalopathy) years and CDC case definition for AIDS-defining conditions: for adolescent and adult, 13 years of age and older (recurrent bacterial pneumonia=3 episodes in 1 year).
b
Virologic failure: persistent viremia (HIV-RNA viral load >1000 copies/mL).