Figure 1.

Pedigree of the family investigated in this study. Individuals II.2 and II.4 had atypical teratoid/rhabdoid tumor (AT/RT). Patient II.4 underwent surgery at the age of two years to resect an AT/RT located in the posterior fossa. Patient II.2 died at the age of one year owing to complications at primary surgery of a SMARCB1‐negative AT/RT. The germline SMARCB1 deletion was detected in patient II.4, her mother and was also in the AT/RT of patient II.2. Consequently, proband I.2 also carries the germline SMARCB1 deletion of exons 8–9