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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Dec 11;142(3):928–941.e8. doi: 10.1016/j.jaci.2017.11.015

FIG 2.

FIG 2.

B-cell development and functionality. A, Relative frequencies of pre-B, immature, and mature recirculating B-cell populations in BM. BMT WT mice, n = 16; BMT OS mice, n = 11; GT 2.6kbUCOE mice, n = 21; GT 2.2kbUCOE mice, n = 7. B, Counts of mature recirculating B cells in BM. C, Counts of B lymphocytes in the spleen. D, Relative frequencies of transitional, marginal, and follicular B-cell populations in the spleen. BMT WT mice, n = 16; BMT OS mice, n = 10; GT 2.6kbUCOE mice, n = 21; GT 2.2kbUCOE mice, n = 7. E, IgM, IgA, IgG, and IgE levels in sera of transplanted mice at the time of 28 weeks. Statistical significance was determined by using the nonparametric combination test (Fig 2, A and D) or nonparametric 1-way ANOVA with the Dunn posttest (Fig 2, B, C, and E). *P < .05, **P < .01, and ***P < .001. All data depicted are means 6 SDs.