Fig. 3.

Otitis media. a Low cuboidal middle ear epithelium and delicate fibrous connective tissue overlying bone in uninvolved middle ear (H&E, 200x). b–d Dense fibrous connective tissue with glandular metaplasia in OM (H&E, 40x). c Fibrous connective tissue between glandular structures (H&E, 100x). d Glandular metaplasia with seromucous secretions (H&E, 200x). e–f Glandular metaplasia set in edematous, granulation type middle ear stroma (H&E 100x). f Higher magnification of glandular metaplasia (H&E, 200x). g Cholesterol clefts within cholesterol granuloma (H&E, 200x). h Foreign body reaction to keratinous debris in keratin granuloma (H&E, 200x). i Uninflamed middle ear ossicle (H&E, 130x)