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. 2017 Sep 12;34(3):430–442. doi: 10.1007/s12288-017-0875-z

Table 8.

Individual patient characteristics of patients with APML with TB

Leukemia characteristics
Serial number Age/sex Hematological diagnosis Therapy Phase of therapy Neutropenia at time of diagnosis of TB Interval (between leukemia and TB) Outcome of leukemia Impact of TB on therapy
P1 28/M APML ATO + ATRA Induction Yes 5 weeks Remission None
P2 28/F APML ATO + ATRA Induction Yes 5 weeks Remission None
P3 30/M APML ATO + ATRA Induction Yes 8 weeks Remission None
P4 55/F APML ATO + ATRA Induction Yes 3 weeks Remission None
P5 29/F APML ATO + ATRA f/b maintenance with 6Mercatopurine and Methotrexate Maintenance Yes 68 weeks Remission None
P6 23/M APML ATO + ATRA Induction Yes Simultaneous Remission None
P7 55/M APML ATO + ATRA Induction Yes 5 weeks Remission None
Tuberculosis characteristics
Serial number Organs involved Site of isolation Evidence of TB Outcome of TB Side effects of ATT Follow up after diagnosis of TB
P1 Lung, mediastinal lymph nodes Mediastinal node FNA AFB positive Improved None In remission at 74 weeks
P2 Lungs, mediastinal nodes Mediastinal node FNA AFB positive Improved None In remission at 64 weeks
P3 Lungs, mediastinal node, pleura Mediastinal node FNA AFB positive Improved Hepatitis In remission at 113 weeks
P4 Lungs, pleura Pleural fluid Clinicoradiologic Improved None In remission at 64 weeks
P5 Lungs, pleura, pericardium, mediastinal lymph nodes, Intestine Pleural, lung, intestine AFB positive Expired TB diagnosed post mortem
P6 Lung BAL fluid AFB positive Improved None 54 weeks
P7 Lung, mediastinal lymph Node Mediastinal Node Gene Xpert positive Improved None 62 weeks

APML acute promyelocytic leukemia, TB tuberculosis, M male, F female, AFB acid fast bacilli, ATO arsenic tri oxide, ATRA all trans retinoic acid, ATT anti tubercular therapy, BAL broncho alveolar lavage, FNA fine needle aspiration