Summary of approaches for cardiac tissue regeneration. The left of this scheme shows the potential cell sources for heart regeneration. The right shows the diagrammatic representation of cardiac patch strategies using biomaterials. In the middle, the diagrammatic representation of the myocardial infarction and the injection methods used in heart regeneration is illustrated. ESCs, embryonic stem cells; CPCs, cardiac progenitor cells; SCs, somatic cells; iPSCs, induced pluripotent stem cells; CMs, cardiomyocytes; CSCs, cardiac stem cells.