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. 2018 Jul;10(Suppl 20):S2333–S2345. doi: 10.21037/jtd.2018.01.117

Table 1. Biomaterials have been investigated for heart regeneration.

Biomaterials Advantages Limitation
Collagen Excellent biocompatibility and biodegradability Low elastic modulus
Chitosan Porosity; high elastic modulus Non-cell adherent
Alginate Gelation capacity; non-thrombogenic property Lack of integration with cardiac cells
Synthetic materials Improved mechanical properties; excellent strength and durability; better uniformity; lower risk of infection Toxicity; low biocompatibility