Table 3.
Summary of results of pharmacokinetic variables from analyses-of-variance: Lactulose 10 g (crystals) vs Water
| Crystals | Lactulose 10 g | Water 250 mL | Treatment difference | |||||
| Variable | n | LS mean | 95%CI | n | LS mean | 95%CI | Difference | 95%CI |
| iAUC (mmol/L*min) | 12 | 6.91 | (-7.41; 21.24) | 12 | 7.74 | (-6.57; 22.05) | -0.822 | (-19.50; 17.85) |
| AUC (mmol/L*min) | 12 | 873.11 | (841.26; 904.97) | 12 | 896.86 | (865.03; 928.70) | -23.75 | (-51.80; 4.30) |
| AUC_base (mmol/L*min) | 12 | -50.14 | (-81.99; -18.28) | 12 | -26.39 | (-58.22; 5.45) | -23.75 | (-51.80; 4.30) |
| C_max (mmol/L) | 12 | 5.32 | (5.12; 5.53) | 12 | 5.36 | (5.16; 5.57) | -0.04 | (-0.30; 0.22) |
| Max_increase (mmol/L) | 12 | 0.20 | (-0.01; 0.40) | 12 | 0.24 | (0.03; 0.44) | -0.04 | (-0.30; 0.22) |