Table 4.

Summary of results of pharmacokinetic variables from analyses-of-variance; Lactulose 20 g (crystals) vs Water

Crystals	Lactulose 20 g			Water 250 mL			Treatment difference
Variable	n	LS mean	95%CI	n	LS mean	95%CI	Difference	95%CI
iAUC (mmol/L*min)	12	12.51	(-1.74; 26.76)	12	7.74	(-6.57; 22.05)	4.772	(-13.58; 23.12)
AUC (mmol/L*min)	12	902.78	(871.02; 934.53)	12	896.86	(865.03; 928.70)	5.912	(-21.48; 33.30)
AUC_base (mmol/L*min)	12	-20.47	(-52.23; 11.28)	12	-26.39	(-58.22; 5.45)	5.912	(-21.48; 33.30)
C_max (mmol/L)	12	5.41	(5.21; 5.62)	12	5.36	(5.16; 5.57)	0.049	(-0.20; 0.30)
Max_increase (mmol/L)	12	0.28	(0.08; 0.49)	12	0.24	(0.03; 0.44)	0.049	(-0.20; 0.30)