Table 1.
Variable | All patients N = 71 | Nodal positive cN+/pN+ N = 24 | Nodal negative cN0/pN0 N = 39 | Occult metastastic cN0/pN+ N = 8 | cN+/pN+ vs. cN0/pN0 P value | cN0/pN0 vs. cN0/pN+ P value | cN+/pN+ vs. cN0/pN+ P value | |
---|---|---|---|---|---|---|---|---|
Age (years) | ||||||||
Median (IQR) | 62 (53–72) | 59 (48–63.75) | 66 (53–74) | 63 (58.25–78.25) | 0.039* | 0.86 | 0.54 | |
Gender | ||||||||
Male | 48 (67.6%) | 19 (79.8%) | 25 (64.1%) | 4 (50.0%) | 0.25 | 0.69 | 0.17 | |
Female | 23 (32.4%) | 5 (20.8%) | 14 (35.9%) | 4 (50.0%) | ||||
Smoking | ||||||||
Yes | 41 (57.7%) | 18 (75.0%) | 20 (51.3%) | 3 (37.5%) | 0.1 | 0.69 | 0.088 | |
No | 30 (42.3%) | 6 (25.0%) | 19 (48.7%) | 5 (62.5%) | ||||
Alcohol | ||||||||
Yes | 29 (40.8%) | 12 (50.0%) | 14 (35.9%) | 3 (37.5%) | 0.17 | 0.68 | 0.69 | |
No | 42 (59.2%) | 12 (50.0%) | 25 (64.1%) | 5 (62.5%) | ||||
Tumor subsite | ||||||||
Oral tongue | 38 (53.5%) | 12 (50.0%) | 21 (53.8%) | 5 (62.5%) | 0.48 | 0.88 | 0.47 | |
Floor of mouth | 26 (36.6%) | 11 (45.8%) | 13 (33.3%) | 2 (25.0%) | ||||
Other | 7 (9.8%) | 1 (4.2%) | 5 (12.9%) | 1 (12.5%) | ||||
T category | ||||||||
pT1 | 13 (18.3%) | 6 (25.0%) | 7 (18%) | 0 (0%) | 0.13 | 0.097 | 0.34 | |
pT2 | 31 (43.7%) | 7 (29.2%) | 21 (53.8%) | 3 (37.5%) | ||||
pT3 | 11 (15.5%) | 4 (16.7%) | 4 (10.3%) | 3 (37.5%) | ||||
pT4 | 16 (22.5%) | 7 (29.2%) | 7 (17.9%) | 2 (25.0%) | ||||
N category | ||||||||
cN+/pN+ | 24 (33.8%) | 24 (100%) | <0.001* | <0.001* | <0.001* | |||
cN0/pN0 | 39 (54.9%) | 39 (100%) | ||||||
cN0/pN+ | 8 (11.3%) | 8 (100%) | ||||||
Dissected nodes | ||||||||
Mean (SEM) | 25.9 (±1.7) | 30.9 (±2.6) | 23.0 (±2.6) | 24.3 (±2.8) | 0.024* | 0.88 | 0.039* | |
Positive nodes | ||||||||
Mean (SEM) | 1.16 (±0.21) | 2.8 (±0.41) | 0 | 2 (±0.38) | <0.001* | <0.001* | 0.62 | |
Largest node (mm) | ||||||||
Mean (SEM) | 7.38 (±1.57) | 20.3 (±3.1) | 0 | 4.1 (±0.76) | <0.001* | <0.001* | <0.003* |
*Statistically significant (p value < 0.05). Iqr: interquartile range. Sem: standard error of mean.
Median test for comparison of continuous variables. Fisher exact test for comparison of categorical variables.