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. 2018 Aug 7;8:11817. doi: 10.1038/s41598-018-30111-7

Table 1.

Baseline Characteristics for Study Cohort and for Study Groups.

Variable All patients N = 71 Nodal positive cN+/pN+ N = 24 Nodal negative cN0/pN0 N = 39 Occult metastastic cN0/pN+ N = 8 cN+/pN+ vs. cN0/pN0 P value cN0/pN0 vs. cN0/pN+ P value cN+/pN+ vs. cN0/pN+ P value
Age (years)
Median (IQR) 62 (53–72) 59 (48–63.75) 66 (53–74) 63 (58.25–78.25) 0.039* 0.86 0.54
Gender
Male 48 (67.6%) 19 (79.8%) 25 (64.1%) 4 (50.0%) 0.25 0.69 0.17
Female 23 (32.4%) 5 (20.8%) 14 (35.9%) 4 (50.0%)
Smoking
Yes 41 (57.7%) 18 (75.0%) 20 (51.3%) 3 (37.5%) 0.1 0.69 0.088
No 30 (42.3%) 6 (25.0%) 19 (48.7%) 5 (62.5%)
Alcohol
Yes 29 (40.8%) 12 (50.0%) 14 (35.9%) 3 (37.5%) 0.17 0.68 0.69
No 42 (59.2%) 12 (50.0%) 25 (64.1%) 5 (62.5%)
Tumor subsite
Oral tongue 38 (53.5%) 12 (50.0%) 21 (53.8%) 5 (62.5%) 0.48 0.88 0.47
Floor of mouth 26 (36.6%) 11 (45.8%) 13 (33.3%) 2 (25.0%)
Other 7 (9.8%) 1 (4.2%) 5 (12.9%) 1 (12.5%)
T category
pT1 13 (18.3%) 6 (25.0%) 7 (18%) 0 (0%) 0.13 0.097 0.34
pT2 31 (43.7%) 7 (29.2%) 21 (53.8%) 3 (37.5%)
pT3 11 (15.5%) 4 (16.7%) 4 (10.3%) 3 (37.5%)
pT4 16 (22.5%) 7 (29.2%) 7 (17.9%) 2 (25.0%)
N category
cN+/pN+ 24 (33.8%) 24 (100%) <0.001* <0.001* <0.001*
cN0/pN0 39 (54.9%) 39 (100%)
cN0/pN+ 8 (11.3%) 8 (100%)
Dissected nodes
Mean (SEM) 25.9 (±1.7) 30.9 (±2.6) 23.0 (±2.6) 24.3 (±2.8) 0.024* 0.88 0.039*
Positive nodes
Mean (SEM) 1.16 (±0.21) 2.8 (±0.41) 0 2 (±0.38) <0.001* <0.001* 0.62
Largest node (mm)
Mean (SEM) 7.38 (±1.57) 20.3 (±3.1) 0 4.1 (±0.76) <0.001* <0.001* <0.003*

*Statistically significant (p value < 0.05). Iqr: interquartile range. Sem: standard error of mean.

Median test for comparison of continuous variables. Fisher exact test for comparison of categorical variables.