Table 1.
SP-, CGRP-, and L-ENK-immunoreactive nerve fibres in various parts of the porcine stomach under physiological conditions (control group) and during experimentally induced diabetes (experimental group).
| Stomach part | Control group | Experimental group | ||||
|---|---|---|---|---|---|---|
| Antrum | Corpus | Pylorus | Antrum | Corpus | Pylorus | |
| SP | ||||||
| Circular muscle layera | 4.82 ± 0.16 | 3.65 ± 0.16 | 6.07 ± 0.13 | 7.42 ± 0.37∗∗ | 5.63 ± 0.15∗∗∗ | 10.75 ± 0.4∗∗∗ |
| Submucosal/mucosal layera | 2.8 ± 0.28 | 5.19 ± 0.20 | 2.41 ± 0.18 | 6.72 ± 0.16∗∗∗ | 9.46 ± 0.41∗∗∗ | 2.89 ± 0.25 |
| CGRP | ||||||
| Circular muscle layera | 6.10 ± 0.08 | 6.20 ± 0.18 | 6.24 ± 0.33 | 10.44 ± 0.26∗∗∗ | 11.38 ± 0.34∗∗∗ | 8.85 ± 0.19 |
| Submucosal/mucosal layera | 2.58 ± 0.12 | 2.08 ± 0.14 | 3.40 ± 0.18 | 2.88 ± 0.18 | 2.45 ± 0.09 | 3.14 ± 0.26 |
| L-ENK | ||||||
| Circular muscle layera | 1.63 ± 0.21 | 3.11 ± 0.22 | 1.78 ± 0.15 | 1.98 ± 0.12 | 1.47 ± 0.37∗∗ | 2.10 ± 0.24 |
| Submucosal/mucosal layera | 1.81 ± 0.24 | 1.43 ± 0.09 | 2.25 ± 0.10 | 1.62 ± 0.51 | 1.58 ± 0.11 | 2.55 ± 0.25 |
Statistically significant data (∗∗P > 0.01 and ∗∗∗P > 0.001). aAverage number of nerve profiles per area (0.55 μm2) studied (mean ± SEM).