Table 3.
The comparison of baseline characteristics between case group and normal group in metabolomics (mean ± SD).
| Variable | Normal group (n=5) | Case group (n=10) | |||
|---|---|---|---|---|---|
| TZQ group (n=5) | placebo group (n=5) | ||||
| mean ± SD | mean ± SD | p | mean±SD | p | |
| Sex (M/F) | 2/3 | 2/3 | 4/1 | ||
| Age (year) | 60.60±1.95 | 62.60±6.43 | 0.524 | 49.80±8.76 | 0.027 |
| BMI (kg/m2) | 20.82±0.92 | 24.92±3.80 | 0.047 | 29.32±4.37 | 0.003 |
| Waistline (cm) | 73.60±4.72 | 93.30±16.10 | 0.031 | 98.40±7.27 | <0.001 |
| HbA1c (%) | 4.66±0.92 | 7.84±0.75 | <0.001 | 7.96±0.71 | <0.001 |
| FINS (mIU/L) | 9.50±4.29 | 16.71±8.87 | 0.140 | 14.66±5.90 | 0.153 |
| FBG (mmol/L) | 4.66±0.50 | 6.89±1.30 | 0.007 | 8.29±1.34 | <0.001 |
| OGTT2hBG (mmol/L) | 9.26±0.92 | 12.38±1.32 | 0.002 | 14.42±1.46 | <0.001 |
| TG (mmol/L) | 1.04±0.06 | 2.24±0.42 | <0.001 | 2.61±0.47 | <0.001 |
| TC (mmol/L) | 3.47±0.68 | 5.29±0.64 | 0.002 | 4.88±0.39 | 0.004 |
| LDL-C (mmol/L) | 1.88±0.61 | 3.06±0.41 | 0.007 | 2.88±0.36 | 0.013 |
| HDL-C (mmol/L) | 1.50±0.22 | 1.21±0.26 | 0.087 | 0.95±0.28 | 0.009 |
Note: data were analyzed using independent sample t test. FBG: fasting blood glucose; OGTT2hBG: oral glucose tolerance test 2 h blood glucose; HbA1c: glycosylated hemoglobin; BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol.