Table 1.
Area (mm2) and wound contraction rate (WCR) (%) in all experimental groups at day 0 and after 7, 14, and 21 days of treatment. Values are mean ± SD.
| C1 | C2 | HF | AL | HF + AL | ||
|---|---|---|---|---|---|---|
| Day 0 | Area | 158.5 ± 26.5 | 153.3 ± 11.6 | 164.5 ± 13.6 | 163.3 ± 12.5 | 160.38 ± 12.6 |
| WCR | 00.00 ± 00.00 | 00.00 ± 00.00 | 00.00 ± 00.00 | 00.00 ± 00.00 | 00.00 ± 00.00 | |
| Day 7 | Area | 76.8 ± 17.6 | 102.8 ± 31.6 | 113.1 ± 13.9∗ | 105.6 ± 8.2∗ | 115.4 ± 14.9∗ |
| WCR | 50.51 ± 12.6 | 29.06 ± 11.7 | 39.77 ± 21.53 | 37.73 ± 13.1 | 31.9 ± 17.4 | |
| Day 14 | Area | 16.8 ± 9.1 | 15.9 ± 9.8 | 36.2 ± 11.9∗ | 30.3 ± 15.4∗ | 38.0 ± 12.3∗ |
| WCR | 88.95 ± 5.5 | 89.16 ± 6.05 | 88.34 ± 7.96 | 81.30 ± 9.1 | 84.70 ± 9.29 | |
| Day 21 | Area | 3.2 ± 4.5 | 2.8 ± 1.7 | 9.1 ± 2.1∗ | 8.18 ± 4.6∗ | 10.4 ± 3.4∗ |
| WCR | 96.73 ± 2.7 | 98.00 ± 1.2 | 94.06 ± 5.35 | 94.96 ± 2.61 | 94.38 ± 5.35 |
C1: control, water via gavage and standard chow diet; C2: control, water (no gavage) and standard chow diet; HF: water (no gavage) and high-fat diet (50%); AL: alcohol (40%) via gavage and standard chow diet; HF + AL: alcohol (40%) via gavage and high-fat diet. ∗ indicates statistical differences versus C1 and C2.