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. 2018 Jul 24;2018:3984068. doi: 10.1155/2018/3984068

Figure 4.

Figure 4

Effect of stigmasterol on TPA-induced ear oedema. Rats received either normal saline (5 ml/kg), polyethylene glycol, PEG (5 ml/kg), dexamethasone, Dex (3 mg/kg), or stigmasterol (10, 50 and 100 mg/kg). Test rats received a topical application of 20 μg TPA dissolved in acetone on each ear daily for 3 days while naïve rats were challenged with acetone only. 5 h after the last TPA or acetone challenge rats were sacrificed and both ears excised to assess oedema in naïve (a), polyethylene glycol, PEG (b), dexamethasone (c), and 10-100 mg/kg stigmasterol-treated groups (d–f). The ear weights were indexed a measure of TPA-induced oedema (g). Data is expressed as mean ear weight (n = 10) ± SEM. ∗∗P < 0.01 and ∗P < 0.05 as compared to PEG-treated TPA-challenged control. ###P < 0.0001 as compared to saline-treated naïve control using one-way ANOVA followed by Dunnett's post hoc test.