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. 2018 Jul 24;2018:3984068. doi: 10.1155/2018/3984068

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Copyright © 2018 Aaron O. Antwi et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of stigmasterol on TPA-induced neutrophilia. Rats received either normal saline (5 ml/kg), polyethylene glycol, PEG (5 ml/kg), dexamethasone, Dex (3 mg/kg), or stigmasterol (10, 50, and 100 mg/kg). Test rats received a topical application of 20 μg TPA dissolved in acetone on each ear daily for 3 days while naïve rats were challenged with acetone only. 5 h after the last TPA or acetone challenge rats were sacrificed and blood collected into EDTA tubes for neutrophil count. Data is expressed as mean neutrophil count (10³ cells/μl) ± SEM. ^∗∗∗P < 0.001 as compared to PEG-treated TPA-challenged control. ^####P < 0.0001 as compared to saline-treated naïve control using one-way ANOVA followed by Dunnett's post hoc test.