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. 2018 Aug 8;3(1):77–82.

Table 1.

Yeast RNA polymerase II subunit genes.

Gene SDS-PACE mobility (kDa) Protein mass (kDa) Stoichiometry Chromosomal location Deletion phenotype Sequence similarity
RPB1 a 220 190 1.1 IV Inviable β′c
RPB2 150 140 1.0 XV Inviable βd
RPB3 45 35 2.1 IX Inviable Human hRPB44e, AC40 f, αf
RPB4 32 25 0.5 X Conditional Acidic region of σ70 g
RPB5 27 25 2.0 II Inviable Human hRPB33h, rpoHi
RPB6 23 18 0.9 XVI Inviable
RPB7 17 19 0.5 IV or XII Inviable
RPB8 14 17 0.8 XV Inviable
RPB9 13 14 2.0 VII Conditional Drosophila 14 kDa proteinj
RPB10 10 8.3l 0.9 XV Inviable
RPB11 13 14 XV Inviable AC19k
RPB12 b 10 7.7 VIII Inviable

a Also known as RP021, RPB220. b Also known as RPC10. c Allison et al., 1985. d Sweetser et al., 1987. e Pati and Weissman, 1990. f Kolodziej and Young, 1989. g Woychik and Young, 1989. h Pati and Weissman, 1989. i Klenk et al., 1992. j Woychik and Young, 1991. k Dequard-Chablat et al., 1991. l The published DNA sequence contained an extra A at position 95 of the open reading frame. The corrected RPB10 sequence extends the open reading frame to encode a protein 70 amino acids in length.