Table 3.
Results from logistic regression model examinining WMH and Alzheimer’s disease neuropathology
| Predicting ADNP: R2 = 0.40; AUC = 0.84 | ||||
|---|---|---|---|---|
| B | Wald Z | p | OR (95 % CI) | |
| Intercept | −13.05 | −2.19 | 0.028 | -- |
| APOE ε4 carrier | 3.39 | 3.75 | < 0.001 | 29.57 (5.04–173.37) |
| Age at death | 0.07 | 1.56 | 0.120 | 1.07 (0.98–1.16) |
| Total brain volume | 0.01 | 2.12 | 0.034 | 1.01 (1.00–1.01) |
| WMH volume | 0.04 | 2.09 | 0.037 | 1.04 (1.00–1.08) |
OR = Odds ratio per unit increase in the predictor. Total brain and WMH volume was measured in cm3.