Table 5.
Cerebrovascular neuropathology among Alzheimer’s disease neuropathology positive and negative individuals
Neuropathology characteristica | ADNP+ | ADNP− | pb |
---|---|---|---|
Infarct or lacune, n (%) | 18 (30.0%) | 9 (40.9%) | 0.505 |
Microinfarct, n (%) | 27 (45.0%) | 10 (45.5%) | 1.000 |
Arteriolosclerosis, n (%) moderate-severe | 34 (57%) | 6 (27%) | 0.035 |
Atherosclerosis, n (%) moderate-severe | 24 (41%) | 8 (38%) | 0.997 |
Cerebral amyloid angiopathy, n (%) moderate-severe |
17 (28%) | 0 | 0.013 |
Abbreviations: SD = standard deviation; ADNP = Alzheimer’s disease neuropathology
Missing data (ADNP+, ADNP−): Atherosclerosis (n=2, n=1)
Significant values were calculated using chi-square tests of independence