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. 2018 Aug 8;25:62. doi: 10.1186/s12929-018-0464-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Impact on GBM cell invasion on targeting IL-8/CXCR1/2 (a) Spheroid invasion assay in U-87MG and LN-18 cell line (b) Graph showing relative invasion of U-87 MG and LN-18 cell lines. The statistically significant decrease in spheroid invasion was observed on day 3 in U-87MG cells treated with Reparixin-l-lysine (p < 0.05). In LN-18 statistically significant difference in spheroid invasion was evident from day 1with p < 0.05, which became even more prominent on day 3 with p < 0.01